Bioorganic Chemistry Lab

1. Aggarwal N, Mandal PK, Gautham N, Chadha A. 2013 Expression, purification, crystallization and preliminary X-ray diffraction analysis of carbonyl reductase
    from Candida parapsilosis ATCC 7330. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69 (Pt 3):313-5. doi: 10.1107/S1744309113003667.
2. Mohanasundaram S.V.,  P. Shyam, N. P. Ratchagar,  A. Chadha, E. Bhattacharya, and S. Pavan “A miniaturized pH sensor with an embedded counter electrode
    and a readout circuit,” IEEE sensors journal, Accepted (21-Jan-2013).

1.  Stella, S., and Chadha, A. (2012) Biocatalytic reduction of α-keto amides to (R)-α-hydroxy amides using Candida parapsilosis ATCC 7330, Catalysis Today
     198, 345-352.
2.  Saravanan, T., Selvakumar, R., Doble, M., and Chadha, A. (2012) Stereochemical preference of Candida parapsilosis ATCC 7330 mediated deracemization:
     E- versus Z-aryl secondary alcohols, Tetrahedron Asymmetry 23, 1360-1368.
3.  Reddy, S. R., Stella, S., and Chadha, A. (2012) Simplified procedure for TEMPO-catalyzed oxidation: Selective oxidation of alcohols, α-hydroxy esters, and
     amides using TEMPO and calcium hypochlorite, Synthetic Communications 42, 3493-3503.

1. Subuddhi, U., Vuram, P. K., Mishra, A. K., and Chadha, A. (2011) Photophysical investigation of microenvironment in glycerol based dansylated polyether
    dendrons, Journal of Photochemistry and Photobiology A: Chemistry 217, 411-416.
2. Saravanan, T., and Chadha, A. (2011) Chemoselective reduction and transesterification of α-keto propargylic esters mediated by NaBH4 and CeCl37H 2O,
    Synthetic Communications 41, 2350-2358.
3. Preetha, R., Rani, K., Veeramani, M. S. S., Fernandez, R. E., Vemulachedu, H., Sugan, M., Bhattacharya, E., and Chadha, A. (2011) Potentiometric estimation
    of blood analytes - Triglycerides and urea: Comparison with clinical data and estimation of urea in milk using an electrolyte-insulator-semiconductor-capacitor
    (EISCAP), Sensors and Actuators, B: Chemical 160, 1439-1443.
4. Mahajabeen, P., and Chadha, A. (2011) One-pot synthesis of enantiomerically pure 1, 2-diols: Asymmetric reduction of aromatic α-oxoaldehydes catalysed by
    Candida parapsilosis ATCC 7330, Tetrahedron Asymmetry 22, 2156-2160.
5. Kumar, G. R., Ravi, R., and Chadha, A. (2011) Kinetic studies of base-catalyzed transesterification reactions of non-edible oils to prepare biodiesel:
    The effect of Co-solvent and temperature, Energy and Fuels 25, 2826-2832.
6. Kaliaperumal, T., Gummadi, S. N., and Chadha, A. (2011) Synthesis of both enantiomers of ethyl-4-chloro-3-hydroxbutanoate from a prochiral ketone using
   Candida parapsilosis ATCC 7330, Tetrahedron Asymmetry 22, 1548-1552.
7. Kaliaperumal, T., Gummadi, S. N., and Chadha, A. (2011) Candida parapsilosis ATCC 7330 can also deracemise 1-arylethanols,
    Biocatalysis and Biotransformation 29, 262-270.
8. Chadha, A., Ravi, R., and Ravikumar, G. (2011) Kinetics of biodiesel production from non-edible vegetable oils.

1.    Vidya, P., and Chadha, A. (2009) The role of different anions in ionic liquids on Pseudomonas cepacia lipase catalyzed transesterification and hydrolysis,
       Journal of Molecular Catalysis B: Enzymatic 57, 145-148.
2.    Vemulachedu, H., Fernandez, R. E., Bhattacharya, E., and Chadha, A. (2009) Miniaturization of EISCAP sensor for triglyceride detection,
       Journal of Materials Science: Materials in Medicine 20, S229-S234.
3.    Mathew, A., Pandian, G., Bhattacharya, E., and Chadha, A. (2009) Novel applications of silicon and porous silicon based EISCAP biosensors,
       Physica Status Solidi (A) Applications and Materials Science 206, 1369-1373.
4.    Fernandez, R. E., Stolyarova, S., Chadha, A., Bhattacharya, E., and Nemirovsky, Y. (2009) MEMS composite porous silicon/polysilicon cantilever sensor
       for enhanced triglycerides biosensing, IEEE Sensors Journal 9, 1660-1666.
5.    Fernandez, R. E., Hareesh, V., Bhattacharya, E., and Chadha, A. (2009) Comparison of a potentiometric and a micromechanical triglyceride biosensor,
       Biosensors and Bioelectronics 24, 1276-1280.

1.    Vaijayanthi, T., and Chadha, A. (2008) Asymmetric reduction of aryl imines using Candida parapsilosis ATCC 7330, Tetrahedron Asymmetry 19, 93-96.
2.    Vaijayanthi, T., and Chadha, A. (2008) Corrigendum to "Asymmetric reduction of aryl imines using Candida parapsilosis ATCC 7330".
       Tetrahedron Asymmetry 19, 765.
3.    Titu, D., and Chadha, A. (2008) Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated
       deracemisation, Journal of Molecular Catalysis B: Enzymatic 52-53, 168-172.
4.    Titu, D., and Chadha, A. (2008) Enantiomerically pure allylic alcohols: preparation by Candida parapsilosis ATCC 7330 mediated deracemisation,
       Tetrahedron Asymmetry 19, 1698-1701.
5.    Fernandez, R. E., Chadha, A., Bhattacharya, E., Stolyarova, S., and Nemirovsky, Y. (2008) MEMS composite porous silicon/polysilicon cantilever sensor
       for enhanced triglycerides biosensing, pp 1468-1471.
6.    Fernandez, R. E., Bhattacharya, E., and Chadha, A. (2008) Covalent immobilization of Pseudomonas cepacia lipase on semiconducting materials,
       Applied Surface Science 254, 4512-4519.

1.    Padhi, S. K., Titu, D., Pandian, N. G., and Chadha, A. (2006) Deracemisation of β-hydroxy esters using immobilised whole cells of Candida parapsilosis ATCC
      7330: substrate specificity and mechanistic investigation, Tetrahedron 62, 5133-5140.
2.    Karmee, S. K., Chandna, D., Ravi, R., and Chadha, A. (2006) Kinetics of base-catalyzed transesterification of triglycerides from Pongamia oil, JAOCS,
       Journal of the American Oil Chemists' Society 83, 873-877.

1.    Padhi, S. K., and Chadha, A. (2005) Deracemisation of aromatic β-hydroxy esters using immobilised whole cells of Candida parapsilosis ATCC 7330
       and determination of absolute configuration by 1H NMR, Tetrahedron Asymmetry 16, 2790-2798.
2.    Karmee, S. K., and Chadha, A. (2005) Rapid and simple method of monoacylation of polyols by β-ketoesters using microwave irradiation,
       Synthetic Communications 35, 1151-1160.
3.    Karmee, S. K., and Chadha, A. (2005) Preparation of biodiesel from crude oil of Pongamia pinnata, Bioresource Technology 96, 1425-1429.
4.    Basu, I., Subramanian, R. V., Mathew, A., Kayastha, A. M., Chadha, A., and Bhattacharya, E. (2005) Solid state potentiometric sensor for the estimation of
       tributyrin and urea, Sensors and Actuators, B: Chemical 107, 418-423.
5.    Baskar, B., Pandian, N. G., Priya, K., and Chadha, A. (2005) Deracemisation of aryl substituted α-hydroxy esters using Candida parapsilosis ATCC 7330:
       Effect of substrate structure and mechanism, Tetrahedron 61, 12296-12306.
6.    Padhi, S. K., Pandian, N. G., and Chadha, A. (2004) Microbial deracemisation of aromatic β-hydroxy acid esters, Journal of Molecular Catalysis B:
       Enzymatic 29, 25-29.
7.    Karmee, S. K., Mahesh, P., Ravi, R., and Chadha, A. (2004) Kinetic study of the base-catalyzed transesterification of monoglycerides from Pongamia oil,
       JAOCS, Journal of the American Oil Chemists' Society 81, 425-430.
8.    Basu, I., Subramanian, R. V., Mathew, A., Chadha, A., and Bhattacharya, E. (2004) Potentiometric biosensors based on silicon and porous silicon,
       pp 224-227.
9.    Baskar, B., Pandian, N. G., Priya, K., and Chadha, A. (2004) Asymmetric reduction of alkyl 2-oxo-4-arylbutanoates and -but-3-enoates by Candida
       parapsilosis ATCC 7330: Assignment of the absolute configuration of ethyl 2-hydroxy-4-(p-methylphenyl)but-3-enoate by 1H NMR,
       Tetrahedron Asymmetry 15, 3961-3966.
10.   Baskar, B., Ganesh, S., Lokeswari, T. S., and Chadha, A. (2004) Highly stereoselective reduction of 4-Aryl-2-oxo but-3-enoic carboxylic esters by plant cell
        culture of Daucus carota, Journal of Molecular Catalysis B: Enzymatic 27, 13-17.
11.   Priya, K., and Chadha, A. (2003) Synthesis of hydrocinnamic esters by Pseudomonas cepacia lipase, Enzyme and Microbial Technology 32, 485-490.
12.   Padhi, S. K., and Chadha, A. (2003) Sodium borohydride reduction and selective transesterification of β-keto esters in a one-pot reaction under mild
       conditions, Synlett, 639-642.
13.   Kumar Reddy, R. R., Basu, I., Bhattacharya, E., and Chadha, A. (2003) Estimation of triglycerides by a porous silicon based potentiometric biosensor,
       Current Applied Physics 3, 155-161.
14.   Priya, K., Venugopal, T., and Chadha, A. (2002) Pseudomonas cepacia lipase - Mediated transesterification reactions of hydrocinnamates,
       Indian Journal of Biochemistry and Biophysics 39, 259-263.
15.   Chadha, A., and Baskar, B. (2002) Biocatalytic deracemisation of α-hydroxy esters: High yield preparation of (S)-ethyl 2-hydroxy-4-phenylbutanoate from the
       racemate, Tetrahedron Asymmetry 13, 1461-1464.
16.   Reddy, R. R., Chadha, A., and Bhattacharya, E. (2001) Porous silicon based potentiometric triglyceride biosensor, Biosensors and Bioelectronics 16,
       313-317.
17.   Reddy, R. R. K., Chadha, A., and Bbattacharya, E. (2000) Porous silicon as a potentiometric biosensor, p I/.
18.   Palani, N., Chadha, A., and Balasubramanian, K. K. (1998) Mechanism of lithium perchlorate/diethyl ether-catalyzed rearrangement of α- and β-endo- and
         -exo-dicyclopentadienyl vinyl ethers: Use of deuterium labeling and a chiral probe, Journal of Organic Chemistry 63, 5318-5323.
19.   Chadha, A., Manohar, M., Soundararajan, T., and Lokeswari, T. S. (1996) Asymmetric reduction of 2-oxo-4-phenylbutanoic acid ethyl ester by Daucus carota
       cell cultures, Tetrahedron Asymmetry 7, 1571-1572.
20.   Chadha, A., and Manohar, M. (1995) Enzymatic resolution of 2-hydroxy-4-phenylbutanoic acid and 2-hydroxy-4-phenylbutenoic acid,
       Tetrahedron Asymmetry 6, 651-652.
21.   Chadha, A., Goergens, U., and Schneider, M. P. (1993) A facile enzyme assisted route to (R)- and (S)-t-butyloxirane and related β-amino alcohols -
       Catalysts for the enantioselective addition of dialkylzinc reagents to aldehydes, Tetrahedron Asymmetry 4, 1449-1450.